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Meta-analysis of randomized controlled studies of closed incisional negative pressure wound therapy versus standard wound dressing in the prevention of surgical site infections for patients undergoing surgeries for lower extremity fractures
1 Fu-Yu Lin, M.D. and Tomas Kempny, M.D.; Ph.D. contributed equally as the first authors.
Fu-Yu Lin
Footnotes
1 Fu-Yu Lin, M.D. and Tomas Kempny, M.D.; Ph.D. contributed equally as the first authors.
Affiliations
Department of Neurology, China Medical University Hospital, School of Medicine, China Medical University, Taichung, TaiwanBig Data Center, China Medical University Hospital, Taichung, Taiwan
1 Fu-Yu Lin, M.D. and Tomas Kempny, M.D.; Ph.D. contributed equally as the first authors.
Tomas Kempny
Footnotes
1 Fu-Yu Lin, M.D. and Tomas Kempny, M.D.; Ph.D. contributed equally as the first authors.
Affiliations
Department of Burns and Plastic Surgery, Institution shared with University Hospital Brno, Faculty of Medicine, Masaryk University, Jihlavská 20, 625 00 Brno, Czech RepublicMEDICent Clinic, Na Ctvrti 22, 70300 Ostrava, Hrabuvka, Czech RepublicFaculty of Medicine, Institute of Emergency Medicine, University of Ostrava, Syllabova 19, 703 00 Ostrava, Czech Republic
Department of Burns and Plastic Surgery, Institution shared with University Hospital Brno, Faculty of Medicine, Masaryk University, Jihlavská 20, 625 00 Brno, Czech RepublicClinic of Plastic and Aesthetic surgery, St. Anne's University Hospital, Faculty of Medicine, Pekarska 664/53, 602 00 Brno, Czech Republic
Correspondence to: Division of Plastic and Reconstructive Surgery, Department of Surgery, Asia University Hospital, Asia University College of Medical and Health Science, Taichung, Taiwan
Division of Plastic and Reconstructive Surgery, Department of Surgery, Asia University Hospital, Asia University College of Medical and Health Science, Taichung, TaiwanDepartment of Food Nutrition and Health Biotechnology, Asia University, Taichung, TaiwanBig Data Center, China Medical University Hospital, Taichung, Taiwan
1 Fu-Yu Lin, M.D. and Tomas Kempny, M.D.; Ph.D. contributed equally as the first authors. 2 Address: No. 222, Fuxin Rd., Wufeng Dist., Taichung City, 41354,Taiwan.
Soft tissue and wound management after lower limb trauma is still an enormously challenging
situation for every surgeon. Negative pressure wound therapy has recently been used
over high-risk closed surgical incisions to decrease surgical-site occurrences, including
wound dehiscence and surgical-site infections (SSIs).
Effect of incisional negative pressure wound therapy vs standard wound dressing on
deep surgical site infection after surgery for lower limb fractures associated with
major trauma: the WHIST randomized clinical trial.
A feasibility study of standard dressings versus negative-pressure wound therapy in
the treatment of adult patients having surgical incisions for hip fractures: the WHISH
randomized controlled trial.
A meta-analysis of randomized controlled studies was performed to evaluate the effectiveness
of ciNPWT in lowering the incidence of SSIs compared to standard wound dressing for
patients undergoing surgeries for lower extremity fractures. (Figure 1).
Figure 1Forest plots demonstrating the risk ratio of ciNPWT versus standard wound dressing
groups in terms of SSIs with random effects model meta-analysis. (ciNPWT: closed incisional
negative pressure wound therapy; SSIs: surgical site infections; M-H, Mantel-Haenszel;
CI: confidence interval).
Effect of incisional negative pressure wound therapy vs standard wound dressing on deep surgical site infection after surgery for lower limb fractures associated with major trauma: the WHIST randomized clinical trial.
A feasibility study of standard dressings versus negative-pressure wound therapy in the treatment of adult patients having surgical incisions for hip fractures: the WHISH randomized controlled trial.
Comparison of vacuum sealing drainage and conventional drainage for postoperative drainage in closed calcaneal fracture: a randomized controlled trial.
