Regional lymph node status in melanoma is an important prognostic factor, where nodal disease carries a less favorable prognosis than localized disease. The sentinel lymph node (SLN) is the first regional lymph node draining the tumor and represents the first site of possible lymphatic metastasis. Sentinel lymph node biopsy (SLNB) for melanoma can be performed using pre-operative lymphoscintigraphy and intra-operative gamma-probe detection or visual identification using an injected dye. A commonly used dye for melanoma in Europe is Patent Blue V (PBV) [Laboratoire Guerbert, Aulnay-Sous-Bois, France]. Its medical use however carries several potential drawbacks, including allergic reactions.
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Published online: February 04, 2023
Accepted: January 29, 2023
Received: October 30, 2022
© 2023 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.