Advertisement
Research Article| Volume 72, ISSUE 4, P555-564, April 2019

Free tissue transfer with the free rectus abdominis flap in high-risk patients above 65 years: A retrospective cohort study

  • Author Footnotes
    1 Both authors contributed equally to this work.
    Benjamin Thomas
    Footnotes
    1 Both authors contributed equally to this work.
    Affiliations
    Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany
    Search for articles by this author
  • Author Footnotes
    1 Both authors contributed equally to this work.
    Emre Gazyakan
    Footnotes
    1 Both authors contributed equally to this work.
    Affiliations
    Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany
    Search for articles by this author
  • Florian Falkner
    Affiliations
    Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany
    Search for articles by this author
  • Volker J. Schmidt
    Affiliations
    Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany
    Search for articles by this author
  • Christoph Hirche
    Affiliations
    Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany
    Search for articles by this author
  • Ulrich Kneser
    Affiliations
    Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany
    Search for articles by this author
  • Amir K. Bigdeli
    Correspondence
    Corresponding author.
    Affiliations
    Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwig-Guttmann-Strasse 13, 67071 Heidelberg, Germany
    Search for articles by this author
  • Author Footnotes
    1 Both authors contributed equally to this work.
Published:January 11, 2019DOI:https://doi.org/10.1016/j.bjps.2019.01.005

      Summary

      Background

      Though technically feasible, free tissue transfer carries the risk of perioperative morbidity and mortality in elderly patients. To minimize the operative treatment time and complication rates, we choose the rectus abdominis muscle (RAM) flap.

      Methods

      Between 2012 and 2017, 34 patients (mean age: 74±7 years, range: 65–89 years) with comorbidities underwent defect reconstruction with a free RAM flap. Recipient-sites were: lower extremity (65%), trunk (18%), upper extremity (12%), and head and neck (6%).

      Results

      The ASA status was 2 in 11 patients, 3 in 21 patients, and 4 in 2 patients. Twenty patients (59%) received additional vascular surgery. Three patients (9%) underwent simultaneous restoration of fractures. The mean operative time (OT) was 325±75 min. There was no total flap loss. Partial flap loss occurred in one patient (3%). The incidence of surgical and medical complications was 32% and 38%: 11 patients experienced a total of 22 surgical complications, of which 15 were major (requiring additional surgery) and 7 minor (conservative treatment). One patient died postoperatively because of progressive respiratory failure. Prolonged OT was highly associated with hematoma formation requiring re-operation (p = 0.01). ASA status was a significant predictor for postoperative critical care monitoring (p = 0.03). Reconstruction was successful in 31 out of 34 patients (91%) during a mean follow-up time of 17.7 ± 8.8 months (range: 2–51 months).

      Conclusion

      The free RAM flap has proven as a reliable and efficient tool in the armamentarium of reconstructive microvascular surgeons with some advantages in the treatment of multimorbid patients older than 65 years.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Plastic, Reconstructive & Aesthetic Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Partridge J.S.
        • Harari D.
        • Dhesi J.K.
        Frailty in the older surgical patient: a review.
        Age Ageing. 2012; 41: 142-147
        • Makary M.A.
        • Segev D.L.
        • Pronovost P.J.
        • et al.
        Frailty as a Predictor of Surgical Outcomes in Older Patients.
        J Am Coll Surg. 2010; 210: 901-908
        • Wong A.K.
        • Nguyen T.J.
        • Peric M.
        • et al.
        Analysis of risk factors associated with microvascular free flap failure using a multi-institutional database.
        Microsurgery. 2015; 35: 6-12
        • Xiong L.
        • Gazyakan E.
        • Kremer T.
        • et al.
        Free flaps for reconstruction of soft tissue defects in lower extremity: a meta-analysis on microsurgical outcome and safety.
        Microsurgery. 2016; 36: 511-524
        • Khouri R.K.
        Free flap surgery. The second decade.
        Clin Plast Surg. 1992; 19: 757-761
        • Wähmann M.
        • Rahimi M.
        • Harhaus L.
        • Kremer T.
        • Kneser U.
        Retrospective analysis of free flaps in elderly patients over 80 years in terms of outcome and complications Retrospektive.
        GMS Ger Plast Reconstr Aesthetic Surg. 2016; 6: 1-3
        • Shestak K.
        • Jones N.
        Microsurgical free-tissue transfer in the elderly patient.
        Plast Reconstr Surg. 1991; 88: 259-263
        • Serletti J.
        • Higgins J.
        • Moran S.
        • Orlando G.
        Factors affecting out- come in free-tissue transfer in the elderly.
        Plast Reconstr Surg. 2000; 106: 66-70
        • Coskunfirat O.K.
        • Chen H.
        • Spanio S.
        • Tang Y.
        The safety of microvascular free tissue transfer in the elderly population.
        Plast Reconstr Surg. 2005; 115: 771-775
        • Salive M.E.
        Multimorbidity in older adults.
        Epidemiol Rev. 2013; 35: 75-83
        • Nielsen C.R.
        • Halling A.
        • Andersen-Ranberg K.
        Disparities in multimorbidity across Europe: findings from the SHARE Survey.
        Eur Geriatr Med. 2017; 8: 16-21
        • Verhelle N.
        • Preud'homme L.
        • Dequanter D.
        • den Hof B.
        • Heymans O.
        • Vico P.
        Free flaps in the elderly population.
        Eur J Plast Surg. 2005; 28: 149-151
        • Aulivola B.
        • Hile C.N.
        • Hamdan A.D.
        • et al.
        Major lower extremity amputation.
        Arch Surg. 2004; 139: 395-399
        • Schuyler Jones W.
        • Patel M.R.
        • Dai D.
        • et al.
        High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease.
        Am Heart J. 2013; 165: 809-815
        • Remes L.
        • Isoaho R.
        • Vahlberg T.
        • et al.
        Major lower extremity amputation in elderly patients with peripheral arterial disease: incidence and survival rates.
        Aging Clin Exp Res. 2008; 20: 385-393
        • Carmona G.
        • Hoffmeyer P.
        • Herrmann F.
        • et al.
        Major lower limb amputations in the elderly observed over ten years: the role of diabetes and peripheral arterial disease.
        Diabetes Metab. 2005; 31: 449-454
        • Xiong L.
        • Gazyakan E.
        • Wähmann M.
        • et al.
        Microsurgical reconstruction for post—traumatic defects of lower leg in the elderly: a comparative study.
        Injury. 2016; 47: 2558-2564
        • Meland N.
        • Fisher J.
        • Irons G.
        • Wood M.
        • Cooney W.
        Experience with 80 rectus abdominis free tissue.
        Plast Reconstr Surg. 1989; 83: 481-487
        • Rao V.
        • Baertsch A.
        Microvascular reconstruction of the upper extremity with the rectus abdominis muscle.
        Microsurgery. 1994; 15: 746-750
        • Horch R.E.
        • Stark G.B.
        The rectus abdominis free flap as an emergency procedure in extensive upper extremity soft-tissue defects.
        Plast Reconstr Surg. 1999; 103: 1421-1427
        • Musharafieh R.
        • Macari G.
        • Hayek S.
        • El Hassan B.
        • Atiyeh B.
        Rectus abdominis free-tissue transfer in lower extremity reconstruction: review of 40 cases.
        J Reconstr Microsurg. 2000; 16: 341-346
        • Tukiainen E.
        • Kallio M.
        • Lepäntalo M.
        Advanced leg salvage of the critically ischemic leg with major tissue loss by vascular and plastic surgeon teamwork: long-term outcome.
        Ann Surg. 2006; 244: 949-957
        • Blondeel N.
        • Vanderstraeten G.G.
        • Monstrey S.J.
        • et al.
        The donor site morbidity of free DIEP flaps and free TRAM flaps for breast reconstruction.
        Br J Plast Surg. 1997; 50: 322-330
        • Sailon A.M.
        • Schachar J.S.
        • Levine J.P.
        Free transverse rectus abdominis myocutaneous and deep inferior epigastric perforator flaps for breast reconstruction: a systematic review of flap complication rates and donor-site morbidity.
        Ann Plast Surg. 2009; 62: 560-563
        • Nahabedian M.Y.
        • Momen B.
        • Galdino G.
        • Manson P.N.
        Breast reconstruction with the free TRAM or DIEP flap: patient selection, choice of flap, and outcome.
        Plast Reconstr Surg. 2002; 110: 466-477
        • Futter C.M.
        • Webster M.H.C.
        • Hagen S.
        • Mitchell S.L.
        A retrospective comparison of abdominal muscle strength following breast reconstruction with a free TRAM or DIEP flap.
        Br J Plast Surg. 2000; 53: 578-583
        • Mennie J.C.
        • Mohanna P.N.
        • O'Donoghue J.M.
        • Rainsbury R.
        • Cromwell D.A.
        Donor-site hernia repair in abdominal flap breast reconstruction: a population-based cohort study of 7929 patients.
        Plast Reconstr Surg. 2015; 136: 1-9
      1. Scheer A.S., Novak C.B., Neligan P.C., Lipa J.E. Complications associated with breast reconstruction using a perforator flap compared with a free TRAM flap.Ann Plast Surg 2006;56(4):355–358.

        • Boehmler J.H.
        • Butler C.E.
        • Ensor J.
        • Kronowitz S.J.
        Outcomes of various techniques of abdominal fascia closure after TRAM flap breast reconstruction.
        Br J Plast Surg. 2000; 53: 578-583
        • Daley B.J.
        • Cecil W.
        • Clarke P.C.
        • Cofer J.B.
        • Guillamondegui O.D.
        How slow is too slow? Correlation of operative time to complications: an analysis from the Tennessee surgical quality collaborative.
        J Am Coll of Surg. 2015; 220: 550-558
        • Cheng H.
        • Po- B.
        • Chen H.
        • et al.
        Prolonged operative duration increases risk of surgical site infections: a systematic review.
        Surg Infect (Larchmt). 2017; 18: 722-735