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Research Article| Volume 72, ISSUE 4, P565-571, April 2019

Surgical outcomes of VRAM versus gracilis flaps for the reconstruction of pelvic defects following oncologic resection

Published:January 09, 2019DOI:https://doi.org/10.1016/j.bjps.2018.12.044

      Summary

      PURPOSE

      Pelvic reconstruction following abdominoperineal resection or pelvic exenteration is associated with signification surgical site morbidity. Immediate pelvic reconstruction with a muscle flap is now the gold standard, associated with reduced perineal morbidity compared to primary closure alone.
      • McAllister E.
      • Wells K.
      • Chaet M.
      • Norman J.
      • Cruse W.
      Perineal reconstruction after surgical extirpation of pelvic malignancies using the transpelvic transverse rectus abdominal myocutaneous flap.
      • Khoo A.K.M.
      • Skibber J.M.
      • Nabawi A.S.
      • et al.
      Indications for immediate tissue transfer for soft tissue reconstruction in visceral pelvic surgery.
      The purpose of the present study was to directly compare outcomes of VRAM and gracilis flap pelvic reconstruction following oncologic resection.

      METHODS

      A multicenter retrospective review was performed of 88 patients who underwent abdominoperineal resection or pelvic exenteration and immediate pelvic reconstruction, either with a VRAM (N = 61) or Gracilis flap (N = 27). Electronic medical records were analyzed for patient demographics, intraoperative data, and postoperative outcomes. Mortality, minor complication rate, major complication rate and time to complete wound healing was compared between groups.

      RESULTS

      Overall, there was no significant difference in the minor complication rate (44% gracilis vs 48% VRAM, p = 0.8), major complication rate (19% gracilis vs 13% of VRAM, p = 0.53), 30-day mortality (0% VRAM vs 0% gracilis, p = 1.0) and median time to complete wound healing (68 days vs 67 days, p = 0.19) between the gracilis and VRAM groups. Muscle-only gracilis flaps had a significantly reduced healing time compared to musculocutaneous gracilis flaps (48 days vs 85 days, p = 0.007).

      CONCLUSIONS

      The workhorse flap in pelvic reconstruction remains the VRAM. While previous studies have alluded to the inferiority of thigh based flaps compared to the VRAM, we demonstrate here that pelvic reconstruction with the gracilis flap can be performed with comparable donor and recipient complication rates and similar time to complete wound healing as the VRAM.

      Keywords

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      References

        • Touran T.
        • Frost D.B.
        • O'Connel T.X.
        Sacral Resection: operative technique and outcome.
        Arch Surg. 1990; 125: 911-913
        • McAllister E.
        • Wells K.
        • Chaet M.
        • Norman J.
        • Cruse W.
        Perineal reconstruction after surgical extirpation of pelvic malignancies using the transpelvic transverse rectus abdominal myocutaneous flap.
        Ann SurgOncol. 1994; 1: 164-168
        • Khoo A.K.M.
        • Skibber J.M.
        • Nabawi A.S.
        • et al.
        Indications for immediate tissue transfer for soft tissue reconstruction in visceral pelvic surgery.
        Surgery. 2001; 130: 463-469
        • Chessin D.B.
        • Hartley J.
        • Cohen A.M.
        • et al.
        Rectus flap reconstruction decreases perineal wound complications after pelvic chemoradiation and surgery: a cohort study.
        Ann SurgOncol. 2005; 12: 104-110
        • Mathes S.J.
        • Feng L.J.
        • Hunt T.K.
        Coverage of the infected wound.
        Ann Surg. 1983; 198 (z): 420-429
        • Baird W.L.
        • Hester T.R.
        • Nahai F.
        • Bostwick III, J.
        Management of perineal wounds following abdominoperineal resection with inferior gluteal flaps.
        Arc Surg. 1990; 125: 1486-1489
        • Anthony J.P.
        • Mathes S.J.
        The recalcitrant perineal wound after rectal extirpation. Application of muscle flap Closure.
        Arch Surg. 1990; 125: 1371-1376
        • Devulapalli C.
        • Wei J.
        • Dibiagio J.R.
        • et al.
        Primary versus Flap closure of perineal defects following oncologic resection: a systematic review and meta analysis.
        Plast Reconstr Surg. May 2016; 137: 1602-1613
        • Ferenschild F.T.
        • Vermaas M.
        • Hofer S.O.
        • Verhoef C.
        • Eggermont A.M.
        • de Wilt J.H.
        Salvage abdominoperineal resection and perienal wound healing in local recurrent or persistent anal cancer.
        Wold J Surg. 2005; 29: 1452-1457
        • Galandiuk S.
        • Jorden J.
        • Mahid S.
        • McCafferty M.H.
        • Tobin G.
        The use of tissue flaps as an adjunct to pelvic surgery.
        AM J Surg. 2005; 190: 186-190
        • Jeon H.
        Comparison of the complications in vertical rectus abdominis musculocutaneous flap with non-reconstructed cases after pelvic exenteration.
        Arch Plast Surg. 2014; 41: 722-727
        • Butler C.E.
        • Gundeslioglu A.O.
        • Rodriguez-Bigas M.A.
        Outocmes of immediate VRAM flap reconstruction of irradiated abdominoperineal resection defects.
        J Am Coll Surg. 2008; 206: 694-703
        • Radice E.
        • Nelson H.
        • Mercill S.
        • Farouk R.
        • Petty P.
        • Gunderson L.
        Primary myocutaneous flap closure following resection of locally advanced pelvic malignancies.
        Br J Surg. 1999; 86 (349–154)
        • Shibata D.
        • Hyland W.
        • Busse P.
        • et al.
        Immediate reconstruction of the perienal wound with gracilis muslce flaps following abdominoperineal resection and intraoperative radation therapy for recurrent carcinoma of the rectum.
        Ann SurgOncol. 1999; 6: 33-37
        • Tae C.
        • Glen B.
        • Kehoe S.
        • Margulis V.
        • Saint-Cyr M.
        Reconstruction of large perineal and pelvic wounds using gracilis muscle flaps.
        Ann Surg Oncol. 2015; 22: 3738-3744
        • Singh M.
        • Kinsley S.
        • Huang A.
        • et al.
        Gracilis flap reconstruction of the perineum: an outcome analysis.
        J Am Coll Surg. 2016; 223: 602-610
      1. SAS and all other SAS Institute Inc. product or service names are registered trademarks or trademarks of SAS Institute Inc. in the USA and other countries. ® indicates USA registration.

        • Johnstone
        Vertical rectus abdominis myocutaneous versus alternative flaps for perineal repair after abdominoperineal excision of the rectum in the era of laparoscopic surgery.
        Annals Plast Surg. July 2017; 79
        • Persichetti P.
        • Cogliandro A.
        • Marangi G.F.
        • et al.
        Pelvic and perineal reconstruction following abdominoperineal resection: the role of gracilis flap.
        Ann Plast Surg. Aug 2007; 59: 168-172
        • Tae C.
        • Glen B.
        • Kehoe S.
        • Margulis V.
        • Saint-Cyr M.
        Reconstruction of large perineal and pelvic wounds using gracilis muscle flaps.
        Ann Surg Oncol. 2015; 22: 3738-3744