Advertisement
Research Article| Volume 65, ISSUE 12, e338-e343, December 2012

Download started.

Ok

The impact of the menstrual cycle on intra-operative and postoperative bleeding in abdominoplasty patients

Published:October 08, 2012DOI:https://doi.org/10.1016/j.bjps.2012.09.001

      Summary

      Background

      Hormonal changes that take place during the menstrual cycle may have an effect on perioperative bleeding. Previous studies have confirmed a relationship between the menstrual cycle and surgical bleeding in rhinoplasty and breast reduction surgery; yet both surgical sites display changes in accordance with sex hormone levels during the menstrual phase.

      Aim

      The aim of this study was to determine the effect of the menstrual cycle on perioperative bleeding when undergoing surgeries of sites not directly related to menstrual hormonal changes.

      Materials and methods

      Forty-one patients undergoing abdominoplasty were grouped as group A – perimenstrual (0–7, 21–28 days), group B – periovulatory (8–20 days) and group C – postmenopausal. Intra-operative blood loss was calculated during surgery while postoperative blood loss was determined by measuring the amount of drainage. All menstrual data were recorded. Age, body mass index and weight of the resected tissue were also considered as factors that can affect the amount of bleeding and therefore were also evaluated in terms of significance.

      Results

      There was no significant difference between groups regarding intra-operative and postoperative blood loss. Body mass index and weight of the resected tissue had a strong influence on the time of drain removal and the amount of intra-operative and postoperative blood loss.

      Conclusion

      This study strongly suggests that the menstrual period does not affect perioperative blood loss for operations on areas less sensitive to sex hormone levels such as the abdomen. In light of the results, we can conclude that the patient's menstrual date is not of vital importance regarding perioperative blood loss when planning surgery for areas with less sensitivity to menstrual hormonal changes.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Plastic, Reconstructive & Aesthetic Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Stewart K.J.
        • Stewart D.A.
        • Coghlan B.
        • Harrison D.H.
        • Jones B.M.
        • Waterhouse N.
        Complications of 278 consecutive abdominoplasties.
        J Plast Reconstr Aesthet Surg. 2006; 59: 1152-1155
        • Wilmink H.
        • Spauwen P.H.
        • Hartman E.H.
        • Hendriks J.C.
        • Koeijers V.F.
        Preoperative injection using a diluted anesthetic/adrenaline solution significantly reduces blood loss in reduction mammaplasty.
        Plast Reconstr Surg. 1998; 102: 373-376
        • Metaxotos N.G.
        • Asplund O.
        • Hayes M.
        The efficacy of bupivacaine with adrenaline in reducing pain and bleeding associated with breast reduction: a prospective trial.
        Br J Plast Surg. 1999; 52: 290-293
        • Villafane O.
        • O'Sullivan S.T.
        • Venkataramakrishnan V.
        Minimising blood loss in reduction mammoplasty by local infiltration of vasoconstrictor agents.
        Br J Plast Surg. 1999; 52: 421-422
        • Liddle A.M.
        • Hall A.P.
        • Arrowsmith J.
        • Smith G.
        Effect of infiltration with ropivacaine on blood loss during reduction mammoplasty.
        Br J Anaesth. 1998; 81: 974-977
        • Thomas S.S.
        • Srivastava S.
        • Nancarrow J.D.
        • Mohmand M.H.
        Dilute adrenaline infiltration and reduced blood loss in reduction mammaplasty.
        Ann Plast Surg. 1999; 43: 127-131
        • Bretteville-Jensen G.
        Mammaplasty with reduced blood loss: effect of noradrenalin.
        Br J Plast Surg. 1974; 27: 31-34
        • Kop E.C.
        • Spauwen P.H.
        • Kouwenberg P.P.
        • Heymans F.J.
        • van Beem H.B.
        Influence of controlled hypotension versus normotension on amount of blood loss during breast reduction.
        J Plast Reconstr Aesthet Surg. 2009; 62: 200-205
        • Ervens J.
        • Marks C.
        • Hechler M.
        • Plath T.
        • Hansen D.
        • Hoffmeister B.
        Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study.
        Int J Oral Maxillofac Surg. 2010; 39: 1168-1174
        • Sariguney Y.
        • Demirtas Y.
        • Findikcioglu F.
        • et al.
        Proper timing of breast reduction during the menstrual cycle.
        Ann Plast Surg. 2004; 53: 528-531
        • Findikcioglu K.
        • Findikcioglu F.
        • Demirtas Y.
        • Yavuzer R.
        • Ayhan S.
        • Atabay K.
        Effect of the menstrual cycle on intraoperative bleeding in rhinoplasty patients.
        Eur J Plast Surg. 2009; 32: 77-81
        • Keith I.
        Anaesthesia and blood loss in total hip replacement.
        Anaesthesia. 1977; 32: 444-450
        • Keith I.
        Ethamsylate and blood loss in total hip replacement.
        Anaesthesia. 1979; 34: 666-670
        • Abrams P.H.
        • Shah P.J.
        • Bryning K.
        • Gaches C.G.
        • Ashken M.H.
        • Green N.A.
        Blood loss during transurethral resection of the prostate.
        Anaesthesia. 1982; 37: 71-73
        • Ramakrishnan R.
        • Khan S.
        • Badve S.
        Morphological changes in breast tissue with menstrual cycle.
        Mod Pathol. 2002; 15: 1348-1356
        • Olsson H.
        • Jernström H.
        • Alm P.
        • et al.
        Proliferation of the breast epithelium in relation to menstrual cycle phase, hormonal use, and reproductive factors.
        Breast Cancer Res Treat. 1996; 40: 187-196
        • Fowler P.A.
        • Casey C.E.
        • Cameron G.G.
        • Foster M.A.
        • Knight C.H.
        Cyclic changes in composition and volume of the breast during the menstrual cycle, measured by magnetic resonance imaging.
        Br J Obstet Gynecol. 1990; 97: 595-602
        • Leimola-Virtanen R.
        • Pennanen R.
        • Syrjänen K.
        • Syrjänen S.
        Estrogen response in buccal mucosa – a cytological and immunohistological assay.
        Maturitas. 1997; 27: 41-45
        • Kramer P.
        • Lubkin V.
        • Potter W.
        • Jacobs M.
        • Labay G.
        • Silverman P.
        Cyclic changes in conjunctival smears from menstruating females.
        Ophthalmology. 1990; 97: 303-307
        • Nir D.
        • Weissman A.
        • Drugan A.
        • et al.
        Effect of estrogen on eustachian tube performance.
        Am J Otol. 1991; 12: 119-121
        • Paulsson B.
        • Gredmark T.
        • Burian P.
        • Bende M.
        Nasal mucosal congestion during the menstrual cycle.
        J Laryngol Otol. 1997; 111: 337-339
        • Ellegard E.
        • Karlsson G.
        Nasal congestion during the menstrual cycle.
        Clin Otolaryngol. 1994; 19: 400-403
        • Navarrete-Palacios E.
        • Hudson R.
        • Reyes-Guerrero G.
        • Guevara-Guzmán R.
        Correlation between cytological characteristics of the nasal epithelium and the menstrual cycle.
        Arch Otolaryngol Head Neck Surg. 2003; 129: 460-463
        • Armengot M.
        • Basterra J.
        • Marco J.
        Nasal mucociliary function during the menstrual cycle in healthy women.
        Rev Laryngol Otol Rhinol. 1990; 111: 107-109
        • Perin F.
        • Pittet J.-C.
        • Schnebert S.
        • Perrier P.
        • Tranquart F.
        • Beau P.
        Ultrasonic assessment of variations in thickness of subcutaneous fat during the normal menstrual cycle.
        Eur J Ultrasound. 2000; 11: 7-14