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Case report| Volume 65, ISSUE 10, e286-e289, October 2012

Tissue expander with acellular dermal matrix for breast reconstruction infected by an unusual pathogen: Candida parapsilosis

  • Paige M. Fox
    Affiliations
    Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Stanford, CA, United States
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  • Gordon K. Lee
    Correspondence
    Corresponding author. Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Stanford Plastic Surgery, 770 Welch Road, Suite 400, MC: 5715, Palo Alto, CA 94304-5715, United States. Tel.: +1 650 723 5824; fax: +1 650 725 6605.
    Affiliations
    Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Stanford, CA, United States
    Search for articles by this author

      Summary

      Infections occur in approximately 2–5% percent of women undergoing breast reconstruction by tissue expansion depending on patient characteristics and timing of reconstruction. Bacteria, specifically Staphylococci, are the most common pathogens. Treatment varies depending on the surgeon and the aggressiveness of the infection. We report a case of unilateral tissue expander infection with Candida parapsilosis in an otherwise healthy female undergoing immediate tissue expander placement after bilateral nipple-sparing mastectomies. The patient was treated with a one-stage irrigation, debridement, and tissue expander exchange as well as a 21-day course of oral antifungal therapy. Her infection resolved and she was able to complete her implant-based reconstruction. C. parapsilosis is usually responsible for infections in critically ill patients found in association with central lines, peritoneal dialysis catheters and prosthetic heart valves. The affinity of C. parapsilosis for foreign material makes it a causative agent worth considering in difficult to treat tissue expander infections.

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