Autologous fat transplantation has gained wide recognition and adoption. Despite an
ever-increasing degree of standardization,
1
many techniques have been advocated and individual factors likely still play a significant
role in the success of this operative technique. It is generally felt that reduced
negative pressure during harvesting adipose tissue leads to a higher grade of graft
viability. Studies have in fact demonstrated the superior viability of adipose tissue
harvested with reduced pressure as compared to conventional suction assisted liposuction.
2
A negative pressure of 760 mmHg has been shown to provoke an adipocyte injury rate
of 90%.
3
The Coleman technique advises using gentle manual syringe liposuction.
4
According to Boyle’s law, negative pressure inside the barrel of the syringe increases
as the volume is enlarged by drawing back on the plunger. The pressure gradient inside
the cannula tip will similarly further increase as the plunger is withdrawn.
5
From a practical perspective we were interested in quantifying the exact negative
pressure inside the syringe at different positions of the plunger. We analysed negative
pressure readings at various plunger positions using standard sterile 10 cc BD Luer
Lock syringes (Byron medical, Mentor, Santa Barbara, CA, USA) and a manual manometer
(VDO, Regensburg, Germany).
Tabled
1
Position [cc] of the plunger of the syringe (n = 10) | Negative pressure [bar] mean ± SD |
Negative pressure [mmHg] mean ± SD |
---|---|---|
1.00 | −0.06 ± 0.01 | −42 ± 7 |
2.00 | −0.14 ± 0.01 | −107 ± 7 |
4.00 | −0.31 ± 0.01 | −223 ± 10 |
5.00 | −0.34 ± 0.01 | −258 ± 4 |
10.00 | −0.52 ± 0.01 | −392 ± 11 |
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References
- Fat grafting to the breast revisited: safety and efficacy.Plast Reconstr Surg. 2007; 119: 775-785
- The viability of autologous fat grafts harvested with the LipiVage system: a comparative study.Ann Plast Surg. 2008; 60: 594-597
- Comparative study of survival of autologous adipose tissue taken and transplanted by different techniques.Plast Reconstr Surg. 1990; 85 (discussion 387–379): 378-386
- Autologous fat grafts harvested and refined by the Coleman technique: a comparative study.Plast Reconstr Surg. 2008; 122: 932-937
- Autologous human fat grafting: effect of harvesting and preparation techniques on adipocyte graft survival.Plast Reconstr Surg. 2006; 117: 1836-1844
Article info
Publication history
Published online: January 24, 2012
Identification
Copyright
© 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Inc. All rights reserved.