Summary
HIV lipoatrophy is a stigmatizing condition associated with significant psychological
morbidity. The aim of this study was to evaluate change in facial volume and psychological
morbidity following treatment with autologous fat, Sculptra® and Bio-alcamid®.
Methods
HIV LD patients were treated based on a clinical assessment in a prospective, observational
study. 3-D images were obtained pre-operatively then at 2, 6 and 12 months post-operatively
using the DI3D system. Volume changes were measured using DI3D software. The DAS-24
and HADS were used to assess psychological morbidity at similar time intervals.
Results
Forty-eight patients with HIV LD were treated: 16 patients had Bio-alcamid®, 20 patients received Sculptra® and 12 patients underwent fat transfer. The mean injected volume of Bio-alcamid® was 25.5 cc which was comparable to the measured volume change at follow-up. The mean injected
volume of fat was 20.1 cc, which did not differ from the measured volumes at 2 months. There was a mean reduction
in measured volume change to11.2 cc at 6 months and 10 cc at 12 months.
For Sculptra®, the mean volume change compared to baseline was 8.7 cc at 2 months, increasing to 12.6 cc at 6 months and 12.3 cc at 12 months.
ANOVA tests demonstrated no difference in psychological outcomes between groups. There
was a significant improvement in DAS-24 scores compared to baseline for all 3 groups.
No correlation between change in facial volume and psychological measures was demonstrated.
Conclusions
Change in 3-D measured facial volume for all 3 groups was seen. Treatment was associated
with improved body image perception.
Keywords
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Article info
Publication history
Published online: December 07, 2011
Accepted:
November 8,
2011
Received:
August 18,
2011
Footnotes
☆Presentations: EURAPS Annual Meeting, Manchester, May 2010, Royal Society of Medicine Facial Reconstruction Meeting, Edinburgh, March 2011.
Identification
Copyright
© 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Inc. All rights reserved.
