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Research Article| Volume 65, ISSUE 1, P29-34, January 2012

Clinical outcome in a series of 173 cases of foreign body granuloma: Improved outcomes with a novel surgical technique

  • Tae Hwan Park
    Affiliations
    Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyung-Dong, Jongno-Gu, Seoul 110-746, South Korea
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  • Sang Won Seo
    Affiliations
    Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyung-Dong, Jongno-Gu, Seoul 110-746, South Korea
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  • June-kyu Kim
    Affiliations
    Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyung-Dong, Jongno-Gu, Seoul 110-746, South Korea
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  • Choong Hyun Chang
    Correspondence
    Corresponding author. Tel.: +82 02 2001 2178; fax: +82 02 2001 2177.
    Affiliations
    Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyung-Dong, Jongno-Gu, Seoul 110-746, South Korea
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Published:September 01, 2011DOI:https://doi.org/10.1016/j.bjps.2011.07.033

      Summary

      Background

      Soft-tissue filler injections have become popular, and injections of even illegal materials are widespread. Complications such as foreign body granuloma often occur in such cases, and appropriate treatment is mandatory but no optimal treatment has been established.

      Methods

      We treated 173 patients who underwent surgical excision of foreign body granulomas via direct approach to the lesion (n = 121) or injection therapies (n = 52) at Kangbuk Samsung Hospital over a period of 7 years from April 2004 to February 2011. A retrospective chart review found that 104 patients had a history of treatment failure at other hospitals. Among these 104 patients, 83 had a history of prior injection therapy and 21 patients had a history of prior surgical therapy. Patient satisfaction was evaluated at our hospital on a scale of 1–5 using an in-house questionnaire. Comparisons between patients receiving injection therapy and patients receiving surgical therapy were made using the Mann–Whitney test.

      Results

      Patients who underwent surgical therapy via direct approach to the lesion reported statistically higher satisfaction scores 4(3–4) than those who underwent injection therapy 3(2–3) (p < 0.001).

      Conclusions

      Our novel surgical technique results in better outcomes and patient satisfaction in cases of severe foreign body granuloma.

      Keywords

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      References

        • Wolfram D.
        • Tzankov A.
        • Piza-Katzer H.
        Surgery for foreign body reactions due to injectable fillers.
        Dermatology. 2006; 213: 300-304
        • Kim H.S.
        • Jeong J.Y.
        • Lee S.R.
        • Shin Y.S.
        • Kim H.S.
        Penile resurfacing after removal of penile foreign body granuloma.
        J Korean Soc Plast Reconstr Surg. 2003; 30: 189-193
        • Kim S.K.
        • Ahn H.C.
        • Jung Y.H.
        The complication and treatment of foreign body injection.
        J Korean Soc Plast Reconstr Surg. 1994; 21: 1148-1159
        • Kwon B.S.
        • Yoon J.H.
        • Kang S.R.
        • Cho M.S.
        Giant dollish face of body dismorphic disorder patient resulting from compulsive foreign body injection.
        J Korean Soc Plast Reconstr Surg. 2003; 30: 668-673
        • Lee Y.S.
        • Choi H.Y.
        • Lew J.M.
        Complications of soft tissue augmentation with injected foreign materials.
        J Korean Soc Plast Reconstr Surg. 1996; 23: 167-180
        • Park T.H.
        • Seo S.W.
        • Kim J.K.
        • Chang C.H.
        The efficacy of perilesional surgical approach for foreign body granuloma.
        Plast Reconstr Surg. 2011; 127: 121e-123e
        • Park T.H.
        • Seo S.W.
        • Kim J.K.
        • Chang C.H.
        Clinical experience with hyaluronic acid-filler complications.
        J Plast Reconstr Aesthet Surg. 2011; 64: 892-896
        • Lemperle G.
        • Gauthier-Hazan N.
        Foreign body granulomas after all injectable dermal fillers: part 2. Treatment options.
        Plast Reconstr Surg. 2009; 123: 1864-1873
        • Rohrich R.J.
        • Monheit G.
        • Nguyen A.T.
        • Brown S.A.
        • Fagien S.
        Soft-tissue filler complications: the important role of biofilms.
        Plast Reconstr Surg. 2010; 125: 1250-1256
        • Rudolph C.M.
        • Soyer H.P.
        • Schuller-Petrovic S.
        • Kerl H.
        Foreign body granulomas due to injectable aesthetic microimplants.
        Am J Surg Pathol. 1999; 23: 113-117
        • Cho S.H.
        • Lee Y.H.
        • Park C.G.
        • Kim C.W.
        Breast reconstruction after removal of paraffinoma.
        J Korean Soc Plast Reconstr Surg. 1984; 11: 67-73
        • Lemperle G.
        • Gauthier-Hazan N.
        • Wolters M.
        • et al.
        Foreign body granulomas after all injectable dermal fillers: part 1. Possible causes.
        Plast Reconstr Surg. 2009; 123: 1842-1863
        • Senet P.
        • Bachelez H.
        • Ollivaud L.
        • Vignon-Pennamen D.
        • Dubertret L.
        Minocycline for the treatment of cutaneous silicone granulomas.
        Br J Dermatol. 1999; 140: 985-987
        • Menon H.
        • Thomas M.
        • D’Silva J.
        Low dose of Hyaluronidase to treat over correction by HA filler–a case report.
        J Plast Reconstr Aesthet Surg. 2010; 63: e416-e417