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Short reports and correspondence| Volume 60, ISSUE 11, P1268-1269, November 2007

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Giant cutaneous horn with naevus sebaceus

      Cutaneous horn (cornu cutaneum) is the clinical description of a hyperproliferation of compact keratin in response to a wide array of underlying benign and malignant pathologic changes.
      • Gould J.W.
      • Brodell R.T.
      Giant cutaneous horn associated with verruca vulgaris.
      A cutaneous horn more than 1 cm in height is rare, because surgeons remove these horns early.
      • Görgü M.
      • Aslan G.
      • Ayhan M.
      • et al.
      Giant cutaneous horn.
      Four main features are associated with a premalignant or malignant histopathological change at the base of a cutaneous horn: patient age, sex, site, and geometry of the lesion. The mean age of patients whose cutaneous horns showed a premalignant or malignant base pathology was 8.9 years older than the mean age of patients in whom the base pathology was benign. Men are more likely to develop a cutaneous horn with a premalignant or malignant base pathology. More than 70% of all premalignant or malignant lesions are found on the nose, pinnae, back of hands, scalp, forearms, and the face, and a cutaneous horn found at these sites is 2:1 times more likely to have been derived from a premalignant or malignant base than from any other part of the body.
      • Yu R.C.
      • Pryce D.W.
      • Macfarlane A.W.
      • et al.
      A histopathological study of 643 cutaneous horns.
      Lesions with a wide base or a low height-to-base ratio were markedly more likely to show a premalignant or malignant base pathology.
      • Yu R.C.
      • Pryce D.W.
      • Macfarlane A.W.
      • et al.
      A histopathological study of 643 cutaneous horns.
      Cornu cutaneum refers to a reaction pattern rather than a specific lesion. Different types of skin lesions underlie cutaneous horns such as keratoses, sebaceous molluscum, verruca, trichilemma, Bowen's disease, epidermoid carcinoma, malignant melanoma, and basal cell carcinoma.
      • Akan M.
      • Yildirim S.
      • Avci G.
      • et al.
      Xeroderma pigmentosum with a giant cutaneous horn.
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      References

        • Gould J.W.
        • Brodell R.T.
        Giant cutaneous horn associated with verruca vulgaris.
        Cutis. 1999; 64: 111-112
        • Görgü M.
        • Aslan G.
        • Ayhan M.
        • et al.
        Giant cutaneous horn.
        Ann Plast Surg. 1999; 43 ([Letter]): 674
        • Yu R.C.
        • Pryce D.W.
        • Macfarlane A.W.
        • et al.
        A histopathological study of 643 cutaneous horns.
        Br J Dermatol. 1991; 124: 449-452
        • Akan M.
        • Yildirim S.
        • Avci G.
        • et al.
        Xeroderma pigmentosum with a giant cutaneous horn.
        Ann Plast Surg. 2001; 46 ([Letter]): 665-666
        • Mencía-Gutiérrez E.
        • Gutiérrez-Díaz E.
        • Redondo-Marcos I.
        • et al.
        Cutaneous horns of the eyelid: a clinicopathological study of 48 cases.
        J Cutan Pathol. 2004; 31: 539-543