Short reports and Correspondence| Volume 60, ISSUE 9, P1079-1080, September 2007

Granulomas of the lips: a rare complication after injection of polylactic acid for aesthetic augmentation

      The demand for lip augmentation continuously increases. Aesthetic injections of the biodegradable filler poly-L-lactic acid (PLA) into lip tissue have been used with good results, but do not always meet patients' expectations. A possible side effect is the development of foreign body granulomas. We present a case which illustrates the pitfalls of PLA injections.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Plastic, Reconstructive & Aesthetic Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Klein A.
        • Elson M.L.
        The history of substances for soft tissue augmentation.
        Dermatol Surg. 2000; 26: 1096-1105
        • Maas C.S.
        • Papel I.D.
        • Greene D.
        • et al.
        Complications of injectable synthetic polymers in facial augmentation.
        Dermatol Surg. 1997; 23: 871-877
        • Ficarra G.
        • Mosqueda–Taylor A.
        • Carlos R.
        Silicone granuloma of the facial tissues: a report of seven cases.
        Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002; 94: 65-73
        • Lombardi T.
        • Samson J.
        • Plantier F.
        • et al.
        Orofacial granulomas after injection of cosmetic fillers. Histopathologic and clinical study of 11 cases.
        J Oral Pathol Med. 2004; 33: 115-120
        • Cheonis N.
        New-Fill to treat facial wasting.
        BETA. 2002; 15: 10-15
        • Kronenthal R.L.
        Biodegradable polymers in medicine and surgery.
        Polym Sci Technol. 1975; 8: 120-137
        • Dijkema S.J.
        • van der Lei B.
        • Kibbelaar R.E.
        New-Fill injections may induce late-onset foreign body granulomatous reaction.
        Plast Reconstr Surg. 2005; 115: 76e-78e
        • Saylan Z.
        Facial fillers and their complications.
        Aesthetic Surg. 2003; 23: 221