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Short reports and Correspondence| Volume 60, ISSUE 8, P965-966, August 2007

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Randomised clinical trials in plastic surgery: Survey of output and quality of reporting

Published:March 16, 2007DOI:https://doi.org/10.1016/j.bjps.2007.01.067
      We were interested to read the article by Karri
      • Karri V.
      Randomised clinical trials in plastic surgery: Survey of output and quality of reporting.
      describing the survey of randomised clinical trials in plastic surgery as we feel this is a research area in which more could and should be done. Of relevance to this review, although not published in the journals covered by the above paper, we have conducted a randomised trial comparing conventional wound dressing against an open dressing involving a herbal medicine-based preparation in 115 patients admitted to hospital for second degree burns.
      • Ang E.S.-W.
      • Lee S.-T.
      • Gan C.S.-G.
      • et al.
      Evaluating the role of alternative therapy in burn wound management: randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second-degree burns.
      • Ang E.S.-W.
      • Lee S.-T.
      • Gan C.S.-G.
      • et al.
      Pain control in a randomized controlled trial comparing Moist Exposed Burn Ointment (MEBO) and conventional methods in patients with partial thickness burns.
      Interestingly, we were able to show very similar wound healing characteristics and pain control with the two strategies despite prior claims of much greater effectiveness of the new approach. In relative terms, this trial was not difficult to design or to conduct, as the options were dressings for the wounds rather than surgical procedures, which contrasts rather markedly with other aspects of the work of a plastic surgery department (much untested in randomised controlled trials, RCTs).
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      References

        • Karri V.
        Randomised clinical trials in plastic surgery: Survey of output and quality of reporting.
        J Plast Reconstr Aesth Surg. 2006; 59: 787-796
        • Ang E.S.-W.
        • Lee S.-T.
        • Gan C.S.-G.
        • et al.
        Evaluating the role of alternative therapy in burn wound management: randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second-degree burns.
        MedGenMed. 2001; 3: 3
        • Ang E.S.-W.
        • Lee S.-T.
        • Gan C.S.-G.
        • et al.
        Pain control in a randomized controlled trial comparing Moist Exposed Burn Ointment (MEBO) and conventional methods in patients with partial thickness burns.
        J Burn Care Rehabil. 2003; 24: 289-296
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        Prerandomization of clinical trials. A more ethical way for performing cleft palate research.
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        New treatment and research strategies for the improvement of care of cleft lip and palate patients in the new millennium.
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