Aims: It is well accepted that Hyaluronic Acid is crucial to wound healing. The aim of this study was to test in-vivo an esterified Hyaluronic Acid scaffold - Hyalomatrix®, to act as a dermal pre-treatment and substitute prior to the application of epidermal replacement in full thickness wounds. Hyalomatrix® is a partial benzyl ester (80% esterified) of Hyaluronic acid coupled with a thin silicone layer providing fluid loss control and a microbial barrier to function as a temporarily epidermis. Investigation of the optimal pre-treatment time was also part of the study.
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© 2007 Published by Elsevier Inc.