Hyalomatrix® – A novel dermal pre-treatment

P. Vaiude; E.T. Anthony; C. Soranzo; S.R. Myers; H.N. Navsaria

doi:10.1016/j.bjps.2007.01.052

Abstract| Volume 60, ISSUE 4, PS14, April 2007

Hyalomatrix^® – A novel dermal pre-treatment

P. Vaiude
P. Vaiude
Affiliations
Plastics & Reconstructive Surgery Department, The Royal London Hospital, Barts & The London NHS Trust, Whitechapel Road, London E1 1BB, UK
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E.T. Anthony
E.T. Anthony
Affiliations
Centre for Cutaneous Research, Barts & The London School of Medicine and Dentistry, Queen Mary, University of London, 1st Floor, ICMS Building, 4 Newark Street, London E1 2AT, UK
Plastics & Reconstructive Surgery Department, The Royal London Hospital, Barts & The London NHS Trust, Whitechapel Road, London E1 1BB, UK
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C. Soranzo
C. Soranzo
Affiliations
Fidia advanced Biopolymers, Padova, Italy
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S.R. Myers
S.R. Myers
Affiliations
Centre for Cutaneous Research, Barts & The London School of Medicine and Dentistry, Queen Mary, University of London, 1st Floor, ICMS Building, 4 Newark Street, London E1 2AT, UK
Plastics & Reconstructive Surgery Department, The Royal London Hospital, Barts & The London NHS Trust, Whitechapel Road, London E1 1BB, UK
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H.N. Navsaria
H.N. Navsaria
Affiliations
Centre for Cutaneous Research, Barts & The London School of Medicine and Dentistry, Queen Mary, University of London, 1st Floor, ICMS Building, 4 Newark Street, London E1 2AT, UK
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DOI:https://doi.org/10.1016/j.bjps.2007.01.052

Aims: It is well accepted that Hyaluronic Acid is crucial to wound healing. The aim of this study was to test in-vivo an esterified Hyaluronic Acid scaffold - Hyalomatrix^®, to act as a dermal pre-treatment and substitute prior to the application of epidermal replacement in full thickness wounds. Hyalomatrix^® is a partial benzyl ester (80% esterified) of Hyaluronic acid coupled with a thin silicone layer providing fluid loss control and a microbial barrier to function as a temporarily epidermis. Investigation of the optimal pre-treatment time was also part of the study.

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DOI: https://doi.org/10.1016/j.bjps.2007.01.052

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