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Abstract| Volume 60, ISSUE 4, PS14, April 2007

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Hyalomatrix® – A novel dermal pre-treatment

  • P. Vaiude
    Affiliations
    Plastics & Reconstructive Surgery Department, The Royal London Hospital, Barts & The London NHS Trust, Whitechapel Road, London E1 1BB, UK
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  • E.T. Anthony
    Affiliations
    Centre for Cutaneous Research, Barts & The London School of Medicine and Dentistry, Queen Mary, University of London, 1st Floor, ICMS Building, 4 Newark Street, London E1 2AT, UK

    Plastics & Reconstructive Surgery Department, The Royal London Hospital, Barts & The London NHS Trust, Whitechapel Road, London E1 1BB, UK
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  • C. Soranzo
    Affiliations
    Fidia advanced Biopolymers, Padova, Italy
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  • S.R. Myers
    Affiliations
    Centre for Cutaneous Research, Barts & The London School of Medicine and Dentistry, Queen Mary, University of London, 1st Floor, ICMS Building, 4 Newark Street, London E1 2AT, UK

    Plastics & Reconstructive Surgery Department, The Royal London Hospital, Barts & The London NHS Trust, Whitechapel Road, London E1 1BB, UK
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  • H.N. Navsaria
    Affiliations
    Centre for Cutaneous Research, Barts & The London School of Medicine and Dentistry, Queen Mary, University of London, 1st Floor, ICMS Building, 4 Newark Street, London E1 2AT, UK
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      Aims: It is well accepted that Hyaluronic Acid is crucial to wound healing. The aim of this study was to test in-vivo an esterified Hyaluronic Acid scaffold - Hyalomatrix®, to act as a dermal pre-treatment and substitute prior to the application of epidermal replacement in full thickness wounds. Hyalomatrix® is a partial benzyl ester (80% esterified) of Hyaluronic acid coupled with a thin silicone layer providing fluid loss control and a microbial barrier to function as a temporarily epidermis. Investigation of the optimal pre-treatment time was also part of the study.
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