Background: A trigger to enhance Full Thickness Wound (FTW) repair is delivery of oxygen and nutritients to the wound site. After the initial inflammatory phase, platelets and keratinocytes (KC) start to secrete Vascular Endothelial Growth Factor (VEGF) to attract Endothelial Cells into the wound granulation tissue. We present a method of ex vivo expansion of autologous KC and lipid mediated gene transfer of a regulable VEGF165 plasmid for the treatment of FTW.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Journal of Plastic, Reconstructive & Aesthetic Surgery
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
© 2007 Published by Elsevier Inc.