Abstract| Volume 60, ISSUE 4, PS4, April 2007

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Porous polyethylene as an endoskeleton for the flexible tissue-engineered auricle

      Introduction: Porous polyethylene (PPE) has been used successfully for craniofacial augmentation and auricular reconstruction. This inert material offers reliable projection and definition and reduced operative time, permitting earlier auricle reconstruction. Tissue engineered auricular cartilage would obviate the current need for costal grafting and its associated morbidity; however it currently lacks biomechanical strength. We propose a composite construct as a model for the tissue engineered auricle, combining the advantages of tissue engineering and alloplast technology. We postulate that PPE could be used as an endoscaffold to support the growth of tissue engineered cartilage and enhance the mechanical properties and morphology of the engineered auricle.
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