Abstract| Volume 60, ISSUE 4, PS4, April 2007

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A bioartifical nerve guide using a resorbable collagen matrix

      Introduction: Reconstruction of peripheral nerve lesions remains a major challenge in plastic surgery. Clinical strategies to treat extensive peripheral nerve injuries include the use of nerve. The goal of the current study is the development of a bioartificially synthesized nerve graft. We present modifications of a specially designed collagen matrix with the attempt to achieve the standard of autologous nerve grafts. The objective is to advance previous in-vivo regeneration results by improving the schwann cell-biomaterial interaction.
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