This paper is only available as a PDF. To read, Please Download here.
Abstract
Eighteen patients with post-burn skin cancers seen at Enugu over an 8-year period have been reviewed. All the tumours were well differentiated squamous cell carcinomas. The mean age of the patients was 36 years and the incubation period of 17.5 years was shorter than in previously reported studies. An aggressive policy in the treatment of these tumours by surgery alone has resulted in an 87% 5-year survival rate for lower limb tumours. When secondary tumours due to pre-existing dermatological diseases are excluded, post-burn skin epitheliomas constituted the largest group of squamous cell skin cancers seen in Enugu, Nigeria.
Reference
- Scar tissue carcinoma. Part 1: A clinical study with special reference to burn scar carcinomas.Annals of Surgery. 1965; 161: 170
- Marjolin's ulcer: an immunologically privileged tumour?.Plastic and Reconstructive Surgery. 1976; 75: 66
- Carcinoma arising in scars, osteomyelitis and fistulae.Archives of Surgery. 1960; 80: 564
- Burn scar malignancy in a possible depressed immunologic setting.in: Surgical Forum. 19. 1968: 511
- Malignancy in scars, chronic ulcers and sinuses.Journal of Clinical Pathology. 1963; 16: 573
- Carcinomatous changes in an area of chronic ulceration, or Marjolin's ulcer.Annals of Surgery. 1903; 37: 496
- The immunobiology of skin cancer.Plastic and Reconstructive Surgery. 1975; 55: 341
- Bulkley lecture: modern attitude toward traumatic cancer.Archives of Pathology. 1935; 19: 690
- Skin cancer in black patients.Cancer. 1975; 35: 600
- Abnormal elastic fibres.Archives of Pathology. 1955; 59: 733
- Epidermoid carcinomas of lower extremities.Archives of Surgery. 1964; 89: 955
- Carcinoma arising in the scars of thermal burns with special reference to the influence of the age at burn on the length of the induction period.Surgery, Gynecology and Obstetrics. 1952; 95: 579
- Ulce`re verruqueux.Dictionnaire de Me´decine. 1828; 21: 46
- Cancer in burn scars (“Marjolin's ulcers”).in: Transactions of the International Society of Plastic Surgeons, 2nd Congress 1959. E & S. Livingstone, Edinburgh1960
- Cicatrical cancer in the South-West of England: a regional plastic unit's experience over a 20-year period.British Journal of Surgery. 1983; 70: 205
- Burns, Pathology and Therapeutic Applications.Butterworths, London1957
- Histochemical studies on squamous cell carcinoma of the skin arising in burn scars with special reference to histogenesis.Indian Journal of Cancer. 1967; 3: 157
- Histochemical and electron microscopic study of epidermal neoplasmas.Indian Journal of Dermatology and Venereology. 1963; 29: 43
- Observations upon the warty ulcer of Marjolin.Dublin Quarterly Journal of Medical Science. 1850; 9: 257
- Scar carcinomas; prognosis and treatment.Southern Medical Journal. 1977; 70: 821
- Analysis of etiological factors of squamous cell skin cancer of different locations.Acta Dermato-Venereologica. 1969; 49: 427
- Epidermoid carcinoma of the extremities with reference to lymph node involvement.Annals of Surgery. 1941; 113: 268
- The development of cancer in burn scars. An analysis and report of 34 cases.Surgery, Gynecology and Obstetrics. 1930; 51: 749
- Minimal criteria to prove causation of traumatic or occupational neoplasms.Annals of Surgery. 1943; 117: 585
Article info
Publication history
Accepted:
April 6,
1987
Received:
October 24,
1986
Identification
Copyright
© 1987 The Trustees of British Association of Plastic Surgeons. All rights reserved. Published by Elsevier Inc.