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Research Article| Volume 46, ISSUE 6, P449-455, 1993

Blood flow through prefabricated flaps—an experimental study in rabbits

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      Summary

      Prefabricated flaps were created by femoral vessel implantation beneath the abdominal skin in rabbits. The area of survival and blood flow through the prefabricated flap were measured after 1, 2, 4, 6, 8, and 12-week intervals. The parameters at 6, 8 and 12-week intervals were significantly larger than those for random pattern flaps (p < 0.01), but were significantly smaller than those for axial pattern flaps (p < 0.01). The minimum interval at which the prefabricated flap could be transferred successfully was between 6 and 8 weeks in this model. Microangiography demonstrated that neovascularisation began at the distal end of the implanted vascular bundle and spread throughout the flap by 8 weeks.

      References

        • McGregor IA
        • Morgan G
        Axial and random pattern flaps.
        Br J Plast Surg. 1973; 26: 202-213
        • Schechter GL
        • Biller HF
        • Ogura JH
        Revascularized skin flaps: a new concept in transfer of skin flaps.
        Laryngoscope. 1969; 79: 1647-1665
        • Ercl OO
        The transformation of a free skin graft into a vascularized pedicled flap.
        Plast Reconst Surg. 1976; 58: 470-477
        • Hori Y
        • Tamai S
        • Okuda H
        • Sakamoto H
        • Takita H
        • Masuhara K
        Blood vessel transplantation to bone.
        J Hand Surg. 1979; 4: 23-33
        • Erol OO
        • Spira M
        Secondary musculocutaneous flap: an experimental study.
        Plast Reconst Surg. 1980; 65: 277-282
        • Erol OO
        • Spira M
        Development and utilization of a composite island flap employing omentum: experimental investigation.
        Plast Reconst Surg. 1980; 65: 405-418
        • Shen TY
        Vascular implantation into skin flap: experimental study and clinical application: a preliminary report.
        Plast Reconst Surg. 1981; 68: 404-409
        • Shintomi Y
        • Ohura T
        The use of muscle vascularized pedicle flaps.
        Plast Reconstr Surg. 1982; 70: 725-734
        • Erk Y
        • Rose FA
        • Spira M
        Vascular augmentation of skin and musculocutaneous flaps.
        Ann Plast Surg. 1983; 10: 341-348
        • Erol OO
        • Spira M
        Reconstructing the breast mound employing a secondary island omental skin flap.
        Plast Reconst Surg. 1990; 86: 510-518
        • Khouri RK
        • Upton J
        • Shaw WW
        Prefabrication of composite free flaps through staged microvascular transfer: an experimental and clinical study.
        Plast Reconst Surg. 1990; 87: 108-115
        • Martinot DV
        • Leps P
        • Schoofs M
        • Patenotre P
        • Pellerin P
        The induced arteriovenous neovascularisation of skin flaps: an experimental study.
        Ann Chir Plast. 1986; 31: 291-298
        • Morrison WA
        • Dvir E
        • Doi K
        • Hurley JV
        • Hickey MJ
        • O'Brien BM
        Prefabrication of thin transferable axial-pattern skin flaps: an experimental study in rabbits.
        Br J Plast Surg. 1990; 43: 645-654
        • Tark CT
        • Khouri RK
        • Shin KS
        • Shaw WW
        The fasciovascular pedicle for revascularisation of other tissues.
        Ann Plast Surg. 1991; 26: 149-155
        • Hale SL
        • Alker KJ
        • Kloner RA
        Evaluation of nonradioactive, colored microspheres for measurement of regional myocardial blood flow in dogs.
        Circulation. 1988; 78: 428-434
        • Nathanson SE
        • Jackson RT
        Blood flow measurements in skin flaps.
        Arch Otolaryngol. 1975; 101: 354-357
        • Guba AM
        • Zinner MJ
        • Hobson RW
        Regional hemodynamics of a pediele flap: evaluation by distribution of radioactive microspheres.
        J Surg Research. 1978; 25: 274-279
        • Pang CY
        • Neligan P
        • Nakatsuka T
        Assessment of microsphere technique for measurement of capillary blood flow in random skin flaps in pigs.
        Plast Reconst Surg. 1984; 74: 513-521
        • Shell W
        • Kligerman M
        • Chang B-L
        • See J
        • Meerbaum S
        • Corday E
        Measurement of myocardial blood flow with non-radioactive microspheres. (Abstract).
        Circulation. 1985; 72: 111-190
        • Inada Y
        • Tamai S
        • Mizumoto S
        • Ono H
        • Kawanishi K
        • Fukui A
        Non-radioactive coloured microsphere measurement of regional tissue blood flow for axial pattern flaps in rabbits.
        Br J Plast Surg. 1993; 46: 127-131
        • Boom MP
        • Saxena PR
        Tissue blood flow changes induced by propranolol infusion in conscious normotensive and renal hypertensive rabbits.
        Arch Int Pharmacodyn. 1983; 264: 109
        • Erdogan E
        Determining the neovascularisation time of secondary island skin flaps: experimental investigations in rats.
        Eur J Plast Surg. 1989; 12: 175-178