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Abstract
A standard burn wound model was developed in the pig to enable evaluation of histopathological parameters of wound healing under different circumstances. Wounds on one flank were treated with silver sulfadiazine 1% cream (SSD, Flammazine-Duphar), which is a standard treatment. On identical places of the contralateral side different topical agents were applied. From the SSD treated burns a typical histopathologic picture of wound healing under SSD could be derived: SSD has the potential to preserve viable dermal tissue, epidermal regeneration is rather slow and irritated, while the formation of granulation tissue is pronounced, with an abundance of myofibroblasts.
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Article info
Publication history
Accepted:
April 16,
1993
Received:
January 13,
1993
Footnotes
This publication was supported by a grant from the Dutch Burns Foundation.
Identification
Copyright
© 1993 The British Association of Plastic Surgeons. Published by Elsevier Inc.