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Abstract
Using 60 Hirosaki hairless rats, the relationship between the time of starting topical administration of Prostaglandin E1 using silicone gel and flap survival rate is described. Compared to control groups, beginning the administration of PGE1 at 0 (P < 0.01) and 3 h (P < 0.05) after flap elevation resulted in an increased flap survival area (Student's t-test). However, in groups in which PGE1 administration was begun at 6, 9 and 12 h after flap elevation, no statistically significant differences could be detected.
Reference
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Article info
Publication history
Accepted:
May 19,
1993
Received:
March 23,
1993
Identification
Copyright
© 1993 The British Association of Plastic Surgeons. Published by Elsevier Inc.
