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Segments of the femoral artery from New Zealand white rabbits were removed and freeze-dried. They were then used as a graft for a defect in the femoral artery of a Sprague-Dawley rat. The femoral artery on the other side of this recipient rat had a similar grafting procedure using a segment of its own femoral artery, thus acting as a control. The patency rate of the freeze-dried heterografts was comparable to the autografts, but the former showed a high incidence of aneurysm formation as a result of immune rejection as supported by histopathological and scanning electron microscopy studies.
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© 1987 The Trustees of British Association of Plastic Surgeons. Published by Elsevier Inc.