Research Article| Volume 33, ISSUE 4, P422-426, October 1980

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The importance of topical heparin in microvascular anastomoses: A study in the rat

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      The importance of heparinised saline irrigation of the vessel ends in microvascular anastomoses may be under-estimated. Recent thrombosis research is reviewed which suggests that heparin is selectively adsorbed onto endothelium, thereby preventing thrombus formation. This evidence is invoked to explain the results of a free flap experiment in the rat and to make some practical recommendations.


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