Journal of Plastic, Reconstructive & Aesthetic Surgery
Volume 63, Issue 4 , Pages e364-e369 , April 2010

The effect of growth hormone on fibroblast proliferation and keratinocyte migration

Received 30 March 2009 ,Accepted 22 October 2009.

References 

  1. Rasmussen LH, Garbarsch C, Schuppan D, et al. Influence of human growth hormone on granulation tissue formation, collagen deposition, and the aminoterminal propeptide of collagen type III in wound chambers in rats. Wound Rep Reg. 1994;2:31–36
  2. Jorgensen PH, Oxlund H. Growth hormone increases the biomechanical strength and collagen deposition rate during the early phase of skin wound healing. Wound Rep Reg. 1996;4:40–47
  3. Scott CD, Martin JL, Baxter RC. Production of insulin-like growth factor-I and its binding protein by adult rat hepatocytes in primary culture. Endocrinology. 1985;116:1094–1101
  4. Pell JM, Bates PC. Differential actions of growth hormone and insulin-like growth factor-1 on tissue protein metabolism in dwarf mice. Endocrinology. 1992;130:1942–1950
  5. Robertson JG, Walton PE, Dunshea F, et al. Growth hormone but not insulin-like growth factor-I improves wound strength in pigs. Wound Rep Reg. 1997;5:168–174
  6. Dunaiski V, Belford DA. Contribution of circulating IGF-1 to wound repair in GH-treated rats. Growth Horm IGF Res. 2002;12:381–387
  7. Steenfos HH, Jansson J-O. Growth hormone stimulates granulation tissue formation and insulin-like growth factor-I gene expression in wound chambers in the rat. J Endocrinol. 1992;132:293–298
  8. Diegelmann RF, Cohen IK, McCoy BJ. Growth kinetics and collagen synthesis of normal skin, normal scar and keloid fibroblasts in vitro. J Cell Physiol. 1979;98:341–346
  9. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65:55
  10. Boyce ST, Ham RG. Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J Invest Dermatol. 1983;81:33s–40s
  11. Li W, Henry G, Fan J, et al. Signals that initiate, augment, and provide directionality for human keratinocyte motility. J Invest Dermatol. 2004;123:622–633
  12. Green H, Morikawa M, Nixon T. A dual effector theory of growth-hormone action. Differentiation. 1985;29:195–198
  13. Losada F, García-Luna PP, Gómez-Cía T, et al. Effects of human recombinant growth hormone on donor-site healing in burned adults. World J Surg. 2002;26:2–8
  14. Steenfos HH. Growth factors and wound healing. Scand J Plast Reconstr Hand Surg. 1994;28:95–105
  15. Singer AJ, Clark RAF. Cutaneous wound healing. N Engl J Med. 1999;341:738–746
  16. Jeschke MG, Schubert T, Krickhahn M, et al. Interaction of exogenous liposomal insulin-like growth factor-I cDNA gene transfer with growth factors on collagen expression in acute wounds. Wound Rep Reg. 2005 May-Jun;13:269–277
  17. Pierre EJ, Perez-Polo R, Mitchell AT, et al. Insulin-like growth factor-1 liposomal gene transfer and systemic growth hormone stimulate wound healing. J Burn Care Rehabil. 1997;18:287–291
  18. Thorey IS, Hinz B, Hoeflich A, et al. Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation. J Biol Chem. 2004;18:26674–26684
  19. Guicheux J, Heymann D, Rousselle AV, et al. Growth hormone stimulatory effects on osteoclastic resorption are partly mediated by insulin-like growth factor I: an in vitro study. Bone. 1998;22:25–31
  20. Merchav S, Tatarsky I, Hochberg Z. Enhancement of erythropoiesis in vitro by human growth hormone is mediated by insulin-like growth factor I. Br J Haematol. 1988;70:267–271
  21. Li JX, Liu XS, Tang H, et al. Influence of some topical antibiotics and FGF2, EGF and rhGH on the biological characteristics of fibroblasts in vitro. Zhonghua Shao Shang Za Zhi. 2006;22:33–37
  22. Kurtz A, Härtl W, Jelkmann W, et al. Activity in fetal bovine serum that stimulates erythroid colony formation in fetal mouse livers is insulin-like growth factor I. J Clin Invest. 1985;76:1643–1648

PII: S1748-6815(09)00752-9

doi: 10.1016/j.bjps.2009.10.027

Journal of Plastic, Reconstructive & Aesthetic Surgery
Volume 63, Issue 4 , Pages e364-e369 , April 2010

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