Journal of Plastic, Reconstructive & Aesthetic Surgery
Volume 60, Issue 6 , Pages 672-681 , June 2007

Comparing conventional gauze therapy to vacuum-assisted closure wound therapy: A prospective randomised trial

  • C.M. Mouës

      Affiliations

    • Department of Plastic and Reconstructive Surgery, Erasmus University Medical Centre, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Reinier de Graaf Gasthuis, Department of Surgery (Resident Plastic Surgery), P.O. Box 5011, 2600 GA Delft, The Netherlands. Tel.: +31 15 2604867; fax: +31 15 2603599.
  • ,
  • G.J.C.M. van den Bemd

      Affiliations

    • Department of Plastic and Reconstructive Surgery, Erasmus University Medical Centre, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands
    • Currently researcher at the Department of Urology, Erasmus University Medical Centre, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.
  • ,
  • F. Heule

      Affiliations

    • Department of Dermatology, Erasmus University Medical Centre, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands
  • ,
  • S.E.R. Hovius

      Affiliations

    • Department of Plastic and Reconstructive Surgery, Erasmus University Medical Centre, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands

Received 24 May 2005 ,Accepted 1 January 2006.

References 

  1. Attinger CE, Bulan EJ. Debridement. The key initial first step in wound healing. Foot Ankle Clin. 2001;6(4):627–660
  2. Schultz GS, Sibbald RG, Falanga V, et al. Wound bed preparation: a systematic approach to wound management. Wound Repair Regen. 2003;11(Suppl. 1):S1–S28
  3. Redon H. La fermeture des plaies etendues sous depression. Presse Med. 1955;63(49):1034
  4. Fleischmann W, Strecker W, Bombelli M, et al. Vacuum sealing as treatment of soft tissue damage in open fractures. Unfallchirurg. 1993;96(9):488–492
  5. Fleischmann W, Lang E, Russ M. Treatment of infection by vacuum sealing. Unfallchirurg. 1997;100(4):301–304
  6. Fleischmann W, Russ M, Westhauser A, et al. Vacuum sealing as carrier system for controlled local drug administration in wound infection. Unfallchirurg. 1998;101(8):649–654
  7. Morykwas MJ, Argenta LC, Shelton-Brown EI, et al. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1997;38(6):553–562
  8. Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997;38(6):563–576[discussion 577]
  9. Wu SH, Zecha PJ, Feitz R, et al. Vacuum therapy as an intermediate phase in wound closure: a clinical experience. Eur J Plast Surg. 2000;23:174–177
  10. DeFranzo AJ, Argenta LC, Marks MW, et al. The use of vacuum-assisted closure therapy for the treatment of lower-extremity wounds with exposed bone. Plast Reconstr Surg. 2001;108(5):1184–1191
  11. Garner GB, Ware DN, Cocanour CS, et al. Vacuum-assisted wound closure provides early fascial reapproximation in trauma patients with open abdomens. Am J Surg. 2001;182(6):630–638
  12. Argenta PA, Rahaman J, Gretz HF, et al. Vacuum-assisted closure in the treatment of complex gynecologic wound failures. Obstet Gynecol. 2002;99(3):497–501
  13. Song DH, Wu LC, Lohman RF, et al. Vacuum assisted closure for the treatment of sternal wounds: the bridge between debridement and definitive closure. Plast Reconstr Surg. 2003;111(1):92–97
  14. Pinocy J, Albes JM, Wicke C, et al. Treatment of periprosthetic soft tissue infection of the groin following vascular surgical procedures by means of a polyvinyl alcohol-vacuum sponge system. Wound Repair Regen. 2003;11(2):104–109
  15. Evans D, Land L. Topical negative pressure for treating chronic wounds: a systematic review. Br J Plast Surg. 2001;54(3):238–242
  16. Joseph E, Hamori CA, Bergman SB, et al. A prospective randomized trial of vacuum assisted closure versus standard therapy of chronic nonhealing wounds. Wounds. 2000;12(3):60–67
  17. McCallon SK, Knight CA, Valiulus JP, et al. Vacuum-assisted closure versus saline-moistened gauze in the healing of postoperative diabetic foot wounds. Ostomy Wound Manage. 2000;46(8):28–34
  18. Ford CN, Reinhard ER, Yeh D, et al. Interim analysis of a prospective, randomized trial of vacuum-assisted closure versus the healthpoint system in the management of pressure ulcers. Ann Plast Surg. 2002;49(1):55–61
  19. Eginton MT, Brown KR, Seabrook GR, et al. A prospective randomized evaluation of negative-pressure wound dressings for diabetic foot wounds. Ann Vasc Surg. 2003;17(6):645–649
  20. Wanner MB, Schwarzl F, Strub B, et al. Vacuum-assisted wound closure for cheaper and more comfortable healing of pressure sores: a prospective study. Scand J Plast Reconstr Surg Hand Surg. 2003;37(1):28–33
  21. Etris MB, Pribble J, LaBrecque J. Evaluation of two wound measurement methods in a multi-center, controlled study. Ostomy Wound Manage. 1994;40(7):44–48
  22. Miller Q, Bird E, Bird K, et al. Effect of subatmospheric pressure on the acute healing wound. Curr Surg. 2004;61(2):205–208
  23. Shah M, Mohanraj M. High levels of fusidic acid-resistant Staphylococcus aureus in dermatology patients. Br J Dermatol. 2003;148(5):1018–1020
  24. Filius PM, Gyssens IC. Impact of increasing antimicrobial resistance on wound management. Am J Clin Dermatol. 2002;3(1):1–7
  25. Lineaweaver W, Howard R, Soucy D, et al. Topical antimicrobial toxicity. Arch Surg. 1985;120(3):267–270
  26. Lineaweaver W, McMorris S, Soucy D, et al. Cellular and bacterial toxicities of topical antimicrobials. Plast Reconstr Surg. 1985;75(3):394–396
  27. Hidalgo E, Bartolome R, Dominguez C. Cytotoxicity mechanisms of sodium hypochlorite in cultured human dermal fibroblasts and its bactericidal effectiveness. Chem Biol Interact. 2002;139(3):265–282
  28. Moues CM, van den Bemd GJ, Meerding WJ, et al. An economic evaluation of the use of TNP on full thickness wounds. J Wound Care. 2005;14(5):224–227
  29. Krasner DL. Managing wound pain in patients with vacuum-assisted closure devices. Ostomy Wound Manage. 2002;48(5):38–43
  30. Lange de MY, Schasfoort RA, Obdeijn MC, et al. Vacuum-assisted closure: indications and clinical experience. Eur J Plast Surg. 2000;23:178–182
  31. Bowler PG. The 10(5) bacterial growth guideline: reassessing its clinical relevance in wound healing. Ostomy Wound Manage. 2003;49(1):44–53
  32. Thomson PD, Smith DJ. What is infection?. Am J Surg. 1994;167(1A):7S–10S[discussion 10S–11S]
  33. Robson MC, Heggers JP. Bacterial quantification of open wounds. Mil Med. 1969;134(1):19–24
  34. Robson MC, Lea CE, Dalton JB, et al. Quantitative bacteriology and delayed wound closure. Surg Forum. 1968;19:501–502
  35. Heller WA, Gottlieb LJ, Zachary LS, et al. The use of quantitative bacteriologic assessment of bone. Plast Reconstr Surg. 1997;100(2):397–401
  36. Breidenbach WC, Trager S. Quantitative culture technique and infection in complex wounds of the extremities closed with free flaps. Plast Reconstr Surg. 1995;95(5):860–865
  37. Isago T, Nozaki M, Kikuchi Y, et al. Negative-pressure dressings in the treatment of pressure ulcers. J Dermatol. 2003;30(4):299–305
  38. Weed T, Ratliff C, Drake DB. Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance?. Ann Plast Surg. 2004;52(3):276–279
  39. Moues CM, Vos MC, van den Bemd GJ, et al. Bacterial load in relation to vacuum-assisted closure wound therapy: a prospective randomized trial. Wound Repair Regen. 2004;12(1):11–17
  40. Clare MP, Fitzgibbons TC, McMullen ST, et al. Experience with the vacuum assisted closure negative pressure technique in the treatment of non-healing diabetic and dysvascular wounds. Foot Ankle Int. 2002;23(10):896–901
  41. Jukema GN, Menon AG, Bernards AT, et al. Amputation-sparing treatment by nature: “surgical” maggots revisited. Clin Infect Dis. 2002;35(12):1566–1571

 This paper was presented, in part, at the sixth European Pressure Ulcer Advisory Panel Open Meeting, September 2002, Budapest, Hungary (poster), at the 13th Annual Educational Symposium of The Wound Healing Society, May 2003, Seattle, USA (oral) and at the 13th European Wound Management Association Conference, May 2003, Pisa, Italy (oral).This work was supported, in part, by the Plastic and Reconstructive Surgery Esser foundation, and KCI Medical, Houten, The Netherlands. The authors have no conflicts of interest to declare.

PII: S1748-6815(06)00348-2

doi: 10.1016/j.bjps.2006.01.041

Journal of Plastic, Reconstructive & Aesthetic Surgery
Volume 60, Issue 6 , Pages 672-681 , June 2007